You should not take more than your prescribed dose and doing so may increase your risk of having a seizure. For bupropion XL, do not take an extra tablet to make up for the dose you forgot. Wait and take your next dose at your regular time the next day.
Avoid drinking alcohol or using illegal drugs while you are taking bupropion because the beneficial effects of the medication may be decreased and the risk of seizures may be increased.
If you are dependent on drugs or alcohol and would like to stop, consult your healthcare provider for help. Abruptly stopping these substances can result in a seizure, especially when taking bupropion. If an overdose occurs, call your doctor or You may need urgent medical care. You may also contact the poison control center at Headache, weight loss, dry mouth, trouble sleeping insomnia , nausea, dizziness, constipation, fast heartbeat, and sore throat.
These will often improve over the first week or two as you continue to take the medication. Unlike many antidepressants, bupropion does not commonly cause sexual side effects and may be selected as an alternative treatment when antidepressant-induced sexual side effects are problematic. Sexual side effects include such problems as difficulty achieving orgasm or ejaculatory delay.
In general the risk of seizures due to bupropion is low. The risk of having a seizure increases with higher than recommended doses of bupropion, a history of seizures or head injury, tumor in the brain, severe liver disease, an eating disorder, alcohol or drug dependence, or taking other drugs that can also increase your risk of having a seizure.
There is a low risk of cardiovascular adverse events associated with stimulating agents, including bupropion. This risk increases if you have heart disease, high blood pressure, previous heart attack, or irregular heartbeat, or when used with transdermal nicotine replacement products. In these cases, a thorough cardiovascular evaluation is recommended before starting this medicine. To date, there are no known problems associated with long term use of bupropion.
It is a safe and effective medication when used as directed. Bupropion should not be taken with or within two weeks of taking monoamine oxidase inhibitors MAOIs. There are several products with the active ingredient bupropion. Do not take more than one product that contains bupropion since this may increase your risk of having a seizure. Certain medications may increase your risk of having a seizure when combined with bupropion.
These include other antidepressants, antipsychotics, theophylline, isoniazid, tramadol, stimulants, steroids, hypoglycemic agents including insulin , certain antibiotics e. These medications can change the way your body reacts to bupropion. Bupropion can change the way your body reacts to these medications.
Sleep, energy, or appetite may show some improvement within the first weeks. Improvement in these physical symptoms can be an important early signal that the medication is working. Depressed mood and lack of interest in actiities may need up to weeks to fully improve. Your doctor may decrease your dose gradually. Bupropion is also sometimes used to treat episodes of depression in patients with bipolar disorder manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods and to treat attention deficit hyperactivity disorder ADHD; more difficulty focusing, controlling actions, and remaining still or quiet than other people who are the same age.
Talk to your doctor about the possible risks of using this medication for your condition. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Skip the missed dose and continue your regular dosing schedule. Always allow the full scheduled amount of time to pass between doses of bupropion. Do not take a double dose to make up for a missed one. Bupropion may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture not in the bathroom.
It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.
However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking bupropion.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. If you are taking the extended-release tablet, you may notice something that looks like a tablet in your stool.
This is just the empty tablet shell and does not mean that you did not get your complete dose of medication. It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
To help avoid interactions, your doctor should manage all of your medications carefully. Do not take these drugs with bupropion. Doing so can cause dangerous effects in your body. Examples of these drugs include:. Taking bupropion with certain medications raises your risk for side effects from these drugs. When bupropion is used with certain drugs, it may not work as well to treat your condition.
This is because the amount of bupropion in your body may be decreased. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Taking it again could be fatal cause death. When taking bupropion, your risk for seizures increases if you have too many drinks that contain alcohol. If you drink alcohol, talk with your doctor about whether this drug is safe for you. For people with a seizure disorder: This drug raises the risk of seizures. You should not take this drug if you have a seizure disorder.
For people with eating disorders such as bulimia or anorexia: This drug raises your risk for seizures. You should not take this drug if you have an eating disorder. For people with bipolar disorder: This drug may make your condition worse. You should not take this drug if you have bipolar disorder.
For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well.
This may increase the levels of this drug in your body and cause more side effects. Your doctor may reduce your dosage of this drug, or how often you are given this drug. For people with liver disease: Your doctor may reduce your dosage of this drug, or how often you are given this drug. For people with angle-closure glaucoma: This drug can make your condition worse. For pregnant women: This drug is a category C pregnancy drug.
That means two things:. This drug should only be used if the potential benefit justifies the potential risk. For women who are breastfeeding: This drug passes into breast milk and may cause side effects in a child who is breastfed.
Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication. For seniors: The kidneys of older adults may not work as well as they used to.
This can cause your body to process drugs more slowly. As a result, a higher amount of a drug stays in your body for a longer time. This raises your risk for side effects. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. It has not been confirmed that this drug is safe and effective for use in people younger than 18 years. This could increase your risk for side effects from these drugs.
Examples of these drugs include:. Other drugs may be less effective when taken with bupropion hydrochloride, such as tamoxifen Soltamox. Because bupropion hydrochloride may cause seizures, it should be used cautiously with drugs that increase your risk for seizures.
Bupropion hydrochloride increases the activity of dopamine a type of brain chemical. Side effects may include restlessness, tremor, dizziness, and agitation. Taking bupropion hydrochloride can increase your blood pressure. These other drugs include:. You should not take bupropion hydrochloride and MOAI drugs within 14 days of each other. In some cases, you may need emergency treatment with linezolid or intravenous IV methylene blue.
If you do, your doctor will typically stop your bupropion hydrochloride treatment and monitor you. You should be able to restart your bupropion hydrochloride treatment 24 hours after your last dose of either drug. No herbs or supplements have been specifically reported to interact with bupropion hydrochloride. However, you should still check with your doctor or pharmacist before using any of these products while taking either medication.
No foods have been specifically reported to interact with bupropion hydrochloride. If you have any questions about eating certain foods with this medication, talk with your doctor. Amphetamines can include illegal drugs and prescription medications used to treat conditions such as attention deficit hyperactivity disorder.
This may occur during or after bupropion hydrochloride treatment. Your doctor will order other tests to confirm whether amphetamines are actually in your urine. To find current prices for either medication in your area, check out GoodRx. The cost you find on GoodRx. Keep in mind that you may be able to get a day supply of the SR or XL form of bupropion hydrochloride ER oral tablets. If approved by your insurance company, getting a day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost.
Before approving coverage for either medication, your insurance company may require you to get prior authorization. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide if the drug will be covered.
Financial assistance may be available to help you pay for the SR or XL form of bupropion hydrochloride ER oral tablets. Medicine Assistance Tool and NeedyMeds are two websites offering resources that may help decrease the price you pay for either medication.
The websites also offer tools to help you find low-cost healthcare, as well as educational resources. To learn more, visit their sites. Some Medicare plans may help cover the cost of mail-order medications. You should take bupropion hydrochloride ER oral tablets according to the instructions your doctor or other healthcare professional gives you. You should take your first dose in the morning. Then you should take your second dose in the afternoon or evening.
Be sure to take your second dose at least 8 hours after your first dose to lower the risk for seizures. If you do, the medication may be released too quickly in your body. This may cause side effects. If you have trouble swallowing the tablets, talk with your doctor or pharmacist right away. You should not skip doses or change your drug regimen.
This is normal and not harmful. In addition, with both forms of the drug, you may see a shell of the tablet in your stool. This is also normal. Your body should have still absorbed the correct amount of the drug. The exact cause of depression is unknown. But experts agree that the condition is partly caused by unbalanced activity of brain chemicals called neurotransmitters. These include serotonin, dopamine , and norepinephrine, which play a role in mood, behavior, and feelings of pleasure.
Antidepressant drugs work by balancing these brain chemicals. Both the SR and XL forms of bupropion hydrochloride ER oral tablets are antidepressants that contain the active drug bupropion hydrochloride.
Bupropion hydrochloride increases the levels of dopamine and norepinephrine in the brain, which may correct an imbalance in the brain. A maintenance dose is the dose you take on a regular basis to keep a steady level of drug in your body. But more information is needed to confirm whether these medications are safe to use while pregnant. Animal studies of the SR and XL forms of bupropion hydrochloride during pregnancy showed conflicting results. They can explain the benefits and risks of using this drug while pregnant as well as the risks of untreated depression.
If you decide to take the SR or XL form of bupropion hydrochloride ER oral tablets during pregnancy, talk with your doctor about joining the pregnancy exposure registry. This service tracks the health effects of taking antidepressant drugs during pregnancy for both those who are pregnant and their children. These details can help doctors and pregnant people make better choices about treating mental health conditions while pregnant.
To learn more, talk with your doctor or visit the National Pregnancy Registry for Antidepressants. They can explain the pros and cons of using either medication while breastfeeding as well as the risks of untreated depression. This drug has a boxed warning. A boxed warning alerts doctors and patients about drug effects that may be dangerous. This includes children, teenagers, and young adults treated with antidepressants for various mental health conditions.
No matter your age, your doctor will monitor you for symptoms of suicidal thoughts and actions during your treatment. You and your loved ones should also watch for any changes in your mood or behavior. Before taking either form of bupropion hydrochloride ER oral tablets SR or XL , talk with your doctor about your health history. These medications may not be right for you if you have certain medical conditions or other factors affecting your health. These include:. Using more than the recommended dosage of the SR or XL form of bupropion hydrochloride ER oral tablets can lead to serious side effects, and in rare cases, death.
You can also call the American Association of Poison Control Centers at or use its online tool.
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